Vitronectin Description

Vitronectin is a admixture of two monomeric glycoproteins (65 and 75 kD) present in claret and the ECM of abounding affiliation tissues. The vitronectin corpuscle bounden area (containing RGD) interacts with vitronectin-specific corpuscle apparent receptors such as integrins αvβ3 and αvβ5. Vitronectin participates in a array of biological processes, including haemostasis, phagocytosis, tissue adjustment and allowed function.
Vitronectin has been used for:
• Promotion of neurite outgrowth
• Chemotaxis of MCF-7 and MDA-MB-435 breast cancer cells
• Promotion of keratinocyte locomotion
• Endothelial cell adhesion
• Derivation and expansion of induced pluripotent stem cells (iPSCs)