Anti-Angiotensinogen antibody function

Essential basic of the renin-angiotensin arrangement (RAS), a almighty regulator of claret pressure, physique aqueous and electrolyte homeostasis. In acknowledgment to bargain claret pressure, the agitator renin cleaves angiotensinogen to aftermath angiotensin-1 (angiotensin 1-10).
Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to crop the physiologically alive peptide angiotensin-2 (angiotensin 1-8). Angiotensin-1 and angiotensin-2 can be added candy to accomplish angiotensin-3 (angiotensin 2-8), angiotensin-4 (angiotensin 3-8). Angiotensin 1-7 is broken from angiotensin-2 by ACE2 or from angiotensin-1 by MME (neprilysin). Angiotensin 1-9 is broken from angiotensin-1 by ACE2.
Angiotensin-2 acts anon on vascular bland beef as a almighty vasoconstrictor, affects cardiac contractility and affection amount through its activity on the affectionate afraid system, and alters renal sodium and baptize assimilation through its adeptness to activate the zona glomerulosa beef of the adrenal case to amalgamate and bury aldosterone.   fa