What is Anti-HPV16 E7 antibody?

Human papilloma bacilli (HPVs) can be classified as either top accident or low accident according to their affiliation with cancer.Approximately 90% of cervical cancers accommodate HPV DNA of the top accident types. Mutational assay accept apparent that the E6 and E7 genes of the top accident HPVs are all-important and acceptable for HPV transforming function.
HPV16 and HPV18 are the a lot of accepted of the top accident accumulation while HPV6 and HPV11 are a part of the low accident types.
The top accident HPV E7 proteins bind to pRB with a college affection than do the low accident HPV proteins, and alone the top accident HPV E6 proteins anatomy apparent complexes with p53 in vitro. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, associate with HPV top and low accident classifications.