Metallothionein expression and regulation

Metallothionein gene announcement is induced by a top array of stimuli, as metal exposure, oxidative stress, glucocorticoids, hydric stress, etc. The akin of the acknowledgment to these inducers depends on the MT gene. MT genes present in their promotors specific sequences for the adjustment of the expression, elements as metal acknowledgment elements (MRE), glucocorticoid acknowledgment elements (GRE), GC-rich boxes, basal akin elements (BLE), and thyroid acknowledgment elements (TRE).