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Specification:100ul/200ul/1ml Description:
Ras GTPase-activating-like protein IQGAP1 is an enzyme that in humans is encoded by the IQGAP1 gene.
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton,…
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Specification:100ul/200ul/1ml Description:
Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene.
This cytokine is produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in…
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Specification:100ul/200ul/1ml Description:
Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes…
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Specification:100ul/200ul/1ml Description:
The DATK32 monoclonal antibody binds to a combinatorial epitope of mouse LPAM -1 (alpha4beta7), which is a heterodimer of the the 154 kDa alpha4 subunit and the 130 kDa beta7 subunit. In mouse, the beta7 subunit is found on the majority of mature lymphocytes and a small population of thymocytes and bone…
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Specification:100ul/200ul/1ml Description:
Integrin αVβ3 (CD51 & CD61) mAB is a primary antibody, which reacts with Integrin αVβ3. Integrins are heterodimeric cell surface receptors composed of a and ? subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial…
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Specification:100ul/200ul/1ml Description:
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD103 / Integrin alpha-E is an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination…
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Specification:100ul/200ul/1ml Description:
Mitogen activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was recently identified and designated ASK1 (for apoptosis signal-regulating kinase 1). ASK1…
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Specification:100ul/200ul/1ml Description:
Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 500 to 14000 Da) proteins. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic) heavy metals through the thiol group of its…